Be careful when going from sitting to standing as blood pressure may drop.The manufacturer states that there is no concern about taking amlodipine with grapefruit juice.Amlodipine is a heart medication that may be used for the treatment of angina or to lower blood pressure but it can cause edema in the ankles or feet.Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. See prescribing information for a full list of drug interactions. May interact with a number of other drugs including those that inhibit hepatic enzymes CYP3A and other drugs that also lower blood pressure.The risk is greater in those with severe obstructive coronary artery disease. Rarely, some patients may experience an increase in the frequency or severity of angina or acute myocardial infarction (heart attack) when starting amlodipine.Blood pressure should be monitored regularly. The risk is higher for people with severe aortic stenosis. ![]() Rarely, excessively low blood pressure may be experienced by some people.When starting treatment in those already on antihypertensive treatment, use a lower starting dose of 2.5 mg/day. Lower doses may be needed in patients with liver disease.Shortness of breath, dizziness, fast or irregular heart beat, flushing, and wheezing have also been reported. Edema (swelling around the ankles) is the main side effect.If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Heart rate at maximal exercise does not change or is slightly reduced. Can improve a person's tolerance to exercise and keep their blood pressure at acceptable levels during exercise.Appears to have little or no interaction with grapefruit or grapefruit products or antacids.In African Americans, calcium channel blockers such as amlodipine may be recommended over other types of heart medications (for example ACE inhibitors, ARBs) for the treatment of hypertension. ![]() Will not relieve acute episodes of angina (other medications such as sublingual nitroglycerin are used for this purpose). May be used as an ongoing treatment to relieve symptoms such as chest pain in people with chronic stable angina, or angina due to coronary artery spasm.May be used for the treatment of high blood pressure (hypertension), alone or in combination with other agents for high blood pressure.Amlodipine belongs to a class of medicines called calcium channel blockers (sometimes called calcium channel antagonists). ![]() Amlodipine does not change the levels of calcium in the blood. The exact way amlodipine works in angina is not known however, experts believe it helps prevent spasm of the coronary artery and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements.
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